SPD Scientific Work Group Participants

Molholm, Sophie, PhD

Title: Professor
Department: Neuroscience, Cognitive Neurophysiology Laboratory
Institution: Albert Einstein College of Medicine of Yeshiva University
Mailing Address: VanEtten Building, Room 1-C, 1225 Morris Park Avenue, Bronx, NY 10461
Phone: (718) 862-1823
sophie.molholm@einstein.yu.edu

Dr. Molholm’s work is focused on sensory processing in the auditory, visual, and somatosensory domains, and the integration of multisensory inputs to form coherent objects. Her work involves characterizing these processes in healthy adults; charting their developmental course over childhood; and translating these findings to understand the neurobiology of developmental disorders, with an emphasis on autism. The primary tools used are high-density electrophysiology and psychophysics. The former allows precise tracking of the temporal progression of cortical information processing, and modeling of the underlying neuronal generators. Used in conjunction with structural and functional neuroimaging and intracranial recordings, part of the toolset used in the lab, precise anatomical localizations of function can be achieved. To complement the translational side of their work, the lab includes a team of senior and junior clinicians that are involved in the phenotyping of participants. Genetic samples are collected from participants with the goal of linking phenotype to genotype, identifying mediating endophenotypic markers. Additional interests of Dr. Molholm’s include investigations into speech processing and comprehension, and attentional influences on information processing.